Around ten percent of most recent Cochrane reviews included outcomes in their literature search strategy and were associated with potentially exaggerated results: A research-on-research study

To assess the proportion of the recent Cochrane reviews that included outcomes in their literature search strategy, how often they acknowledged these limitations, and how qualitatively different the results of outcomes included and not included in the search strategy were. We identified all the Coch...

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Veröffentlicht in:Journal of clinical epidemiology 2022-01, Vol.141, p.74-81
Hauptverfasser: Tsujimoto, Yasushi, Tsutsumi, Yusuke, Kataoka, Yuki, Banno, Masahiro, Furukawa, Toshi A.
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container_start_page 74
container_title Journal of clinical epidemiology
container_volume 141
creator Tsujimoto, Yasushi
Tsutsumi, Yusuke
Kataoka, Yuki
Banno, Masahiro
Furukawa, Toshi A.
description To assess the proportion of the recent Cochrane reviews that included outcomes in their literature search strategy, how often they acknowledged these limitations, and how qualitatively different the results of outcomes included and not included in the search strategy were. We identified all the Cochrane reviews of the interventions published in 2020 that used a search strategy connecting outcome terms with “AND.” Reviews were defined as acknowledging the limitations of searching for outcomes if they mentioned them in the discussion. We compared the characteristics of outcomes included and not included in the search strategy. Of the 523 Cochrane reviews published in 2020, 51 (9.8%) included outcomes in their search strategy. Only one review acknowledged it as a limitation. Forty-seven (92%) assessed outcomes not included in the search strategy. Outcomes included in the search strategies tended to include a larger number of studies and show their effects in favor of the intervention. Around ten percent of the recent Cochrane reviews included outcomes in their search, which may have resulted in more outcomes significantly in favor of the intervention. Reviewers should be more explicit in acknowledging the potential implications of searching for outcomes.
doi_str_mv 10.1016/j.jclinepi.2021.08.030
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subjects Bias
Epidemiology
Meta-analysis
meta-epidemiology
publication bias
Reviews
Search methods
search strategy
selective outcome reporting
Systematic review
title Around ten percent of most recent Cochrane reviews included outcomes in their literature search strategy and were associated with potentially exaggerated results: A research-on-research study
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