Structural Basis for Anti-non-alcoholic Fatty Liver Disease and Diabetic Dyslipidemia Drug Saroglitazar as a PPAR α/γ Dual Agonist

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptor-type transcription factors that consist of three subtypes (α, γ, and β/δ) with distinct functions and PPAR dual/pan agonists are expected to be the next generation of drugs for metabolic diseases. Saroglitazar is the first clin...

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Veröffentlicht in:Biological & pharmaceutical bulletin 2021/09/01, Vol.44(9), pp.1210-1219
Hauptverfasser: Honda, Akihiro, Kamata, Shotaro, Satta, Chihiro, Machida, Yui, Uchii, Kie, Terasawa, Kazuki, Nemoto, Ayane, Oyama, Takuji, Ishii, Isao
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Sprache:eng
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