Origin of Enantioselectivity in Chiral Phosphoric-Acid-Catalyzed Azlactone Dynamic Kinetic Resolution

Theoretical calculations, associated with control experiments, were carried out to gain insights into the mechanism and origin of enantioselectivity in the phosphoric-acid-catalyzed dynamic kinetic resolution of azlactones. The results revealed a Münchnone intermediate as the key species involved i...

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Veröffentlicht in:	Journal of organic chemistry 2021-09, Vol.86 (18), p.13169-13174
Hauptverfasser:	De Castro, Pedro P, Batista, Gabriel M. F, Amarante, Giovanni W, Dos Santos, Hélio F
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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