Behavioural adaptations after antibiotic treatment in male mice are reversed by activation of the aryl hydrocarbon receptor

•The intestinal microbiota is a fundamental modulator of brain functions and behaviour.•Depletion of intestinal microbiota using antibiotics alters despair behaviour in adult male mice.•Spontaneous microbiota recolonization after antibiotic treatment normalized behaviour.•Aryl hydrocarbon receptor a...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2021-11, Vol.98, p.317-329
Hauptverfasser:	Vicentini, Fernando A., Mathews, Alexander J., Pittman, Quentin J., Swain, Mark G., Sharkey, Keith A., Hirota, Simon A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Cytochrome P-450 CYP1A1 Depression Despair Female Gastrointestinal Microbiome Male Mice Mice, Knockout Microbiota Microbiota-gut-brain axis Receptors, Aryl Hydrocarbon β-naphthoflavone
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