Early Clostridioides difficile infection characterizations, risks, and outcomes in allogeneic hematopoietic stem cell and solid organ transplant recipients

Background Clostridioides difficile infection (CDI) frequently complicates allogeneic hematopoietic stem cell (allo‐HCT) and solid organ transplantation (SOT). Methods We retrospectively analyzed risk factors and outcomes of CDI occurring within 30 days of transplant. Results Between March 2010 and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Transplant infectious disease 2022-02, Vol.24 (1), p.e13720-n/a
Hauptverfasser:	Obeid, Karam M., Sapkota, Smarika, Cao, Qing, Richmond, Steven, Watson, Allison P., Karadag, Fatma Keklik, Young, Jo‐Anne H., Pruett, Timothy, Weisdorf, Daniel J., Ustun, Celalettin
Format:	Artikel
Sprache:	eng
Schlagworte:	allogeneic hematopoietic stem cell transplant Clostridioides difficile Clostridioides difficile infection Clostridium Infections - epidemiology Fluoroquinolones Heart transplantation Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cells Humans Kidney transplantation mortality Multivariate analysis Organ Transplantation - adverse effects outcomes rates Retrospective Studies Risk analysis Risk factors solid organ transplant Stem cells Survival Thorax Transplant Recipients Transplantation Transplants & implants
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Background Clostridioides difficile infection (CDI) frequently complicates allogeneic hematopoietic stem cell (allo‐HCT) and solid organ transplantation (SOT). Methods We retrospectively analyzed risk factors and outcomes of CDI occurring within 30 days of transplant. Results Between March 2010 and June 2015, 466 allo‐HCT and 1454 SOT were performed. The CDI cumulative incidence (95% CI) was 10% (8–13) and 4% (3–5), following allo‐HCT and SOT, respectively (p
ISSN:	1398-2273 1399-3062
DOI:	10.1111/tid.13720