Alantolactone exhibits antiproliferative and apoptosis-promoting properties in colon cancer model via activation of the MAPK-JNK/c-Jun signaling pathway

Colorectal cancer (CRC) is one of the most common human malignancies in the digestive tract with high mortality. Alantolactone (ATL), as a plant-derived sesquiterpene lactone, has shown a variety of pharmacological activities, such as antibacterial, anti-inflammatory, anti-virus and so on. However,...

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Veröffentlicht in:Molecular and cellular biochemistry 2021-12, Vol.476 (12), p.4387-4403
Hauptverfasser: Ren, Yijing, Lv, Cheng, Zhang, Jing, Zhang, Beibei, Yue, Bei, Luo, Xiaoping, Yu, Zhilun, Wang, Hao, Ren, Junyu, Wang, Zhengtao, Dou, Wei
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Sprache:eng
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