Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2H-indazole Hybrids

Cancer is the second leading cause of death, after cardiovascular diseases. Different strategies have been developed to treat cancer; however, chemotherapy with cytotoxic agents is still the most widely used treatment approach. Nevertheless, drug resistance to available chemotherapeutic agents is st...

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Veröffentlicht in:	Pharmaceuticals (Basel, Switzerland) Switzerland), 2021-08, Vol.14 (8), p.815
Hauptverfasser:	Pérez-Villanueva, Jaime, Matadamas-Martínez, Félix, Yépez-Mulia, Lilián, Pérez-Koldenkova, Vadim, Leyte-Lugo, Martha, Rodríguez-Villar, Karen, Cortés-Benítez, Francisco, Macías-Jiménez, Ana Perla, González-Sánchez, Ignacio, Romero-Velásquez, Ariana, Palacios-Espinosa, Juan Francisco, Soria-Arteche, Olivia
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites cancer Cancer therapies combretastatin A-4 cytotoxic activity Cytotoxicity hybrid compounds indazole Leukemia Lung cancer Mass spectrometry NMR Nuclear magnetic resonance Scientific imaging
Online-Zugang:	Volltext
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