Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring

Most infections that occur during pregnancy are mild and transient. However, whether such pathogen encounters can shape the long-term trajectory of the offspring’s immune system remains unclear. Lim et al . infected pregnant mice with the common food-borne pathogen Yersinia pseudotuberculosis (YopM)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 2021-08, Vol.373 (6558)
Hauptverfasser:	Lim, Ai Ing, McFadden, Taryn, Link, Verena M., Han, Seong-Ji, Karlsson, Rose-Marie, Stacy, Apollo, Farley, Taylor K., Lima-Junior, Djalma S., Harrison, Oliver J., Desai, Jigar V., Lionakis, Michail S., Shih, Han-Yu, Cameron, Heather A., Belkaid, Yasmine
Format:	Artikel
Sprache:	eng
Schlagworte:	Accessibility Adaptive systems Adults Antigen presentation Antigens Antiinfectives and antibacterials Antimicrobial peptides Chromatin Clonal deletion Colitis Context Cytokines Developmental stages Dextran Dextran sulfate Dextrans Digestive system Disorders Epigenetics Epithelium Exposure Fetuses Fitness Food Gastrointestinal tract Gene expression Gene sequencing Homeostasis Immune system Immunity Immunological memory Imprinting Infections Inflammation Inflammatory bowel disease Inflammatory diseases Injection Interleukin 6 Intestine Long-term effects Lymphocytes Lymphocytes T Microbiota Microorganisms Offspring Pathogens Peptides Pregnancy Prenatal development Prenatal Influences Salmonella Salmonella Typhimurium Stem cells Tissues Weaning Yersinia pseudotuberculosis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!