Application of T cell receptor (TCR) repertoire analysis for the advancement of cancer immunotherapy

•TCR repertoire analysis as a tool to advance cancer immunotherapy.•Computational methods are used to understand TCR repertoire characteristics.•Both TCR sequence and structure have been used for specificity prediction. T cell receptor (TCR) sequencing has emerged as a powerful new technology in ana...

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Veröffentlicht in:	Current opinion in immunology 2022-02, Vol.74, p.1-8
Hauptverfasser:	Joshi, Kroopa, Milighetti, Martina, Chain, Benjamin M
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Immunotherapy Immunotherapy, Adoptive Neoplasms - therapy Receptors, Antigen, T-Cell - genetics T-Lymphocytes
Online-Zugang:	Volltext
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