Comparison of Pharmacokinetics and Tissue Distribution Characteristics of Three Diterpenoid Esters in Crude and Prepared Semen Euphorbiae

Background. Semen Euphorbiae (SE) and Semen Euphorbiae Pulveratum (SEP) have a long history of medicinal use. SEP is the processed product of SE; both ancient and modern studies have shown that SEP has a lower toxicity compared to SE. To clarify the influence of processing on the pharmacological pro...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2021, Vol.2021, p.7402120-11, Article 7402120
Hauptverfasser:	Wang, Hui-Nan, Wang, Pei-Hua, Yang, Zi-Ye, Zhang, Gui-Mei, Chen, Meng-Yu, Jiang, Ming-Rui, Yue, Zhu-Zhu, Wang, Zhi-Cheng, Zhang, Jing-Qiu, Cao, Yan-Hua, An, Hong, Wang, Ying-Zi
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Acetic acid Animals Biotechnology industry Chinese medicine Colon Diterpenes Esters Ethyl acetate Euphorbia Formic acid Gas flow Integrative & Complementary Medicine Kidneys Laxatives Life Sciences & Biomedicine Liver Oral administration Pharmacokinetics Plasma Quality control Science & Technology Spleen Toxicity
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