Trophic factors as potential therapies for treatment of major mental disorders

•The majority of neuropsychiatric disorders are associated with alterations in neuroplasticity.•Neuroplasticity is regulated by trophic factors and by neurotrophins in particular.•Action mechanisms of psychoactive drugs involve changes in neurotrophic signalling.•Exogenous neurotrophins might confer...

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Veröffentlicht in:	Neuroscience letters 2021-11, Vol.764, p.136194-136194, Article 136194
Hauptverfasser:	Dremencov, Eliyahu, Jezova, Daniela, Barak, Segev, Gaburjakova, Jana, Gaburjakova, Marta, Kutna, Viera, Ovsepian, Saak V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressants Antipsychotics Disease Models, Animal Drug Evaluation, Preclinical Growth factor Humans Mental Disorders - drug therapy Nanoparticle Drug Delivery System Nerve Growth Factors - administration & dosage Neuronal Plasticity - drug effects Neuropsychiatry Polyplex nanoparticles Review Literature as Topic Targeted delivery
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