Bicyclic Pyrrolidines for Medicinal Chemistry via [3 + 2]-Cycloaddition

A general approach to bicyclic fused pyrrolidines via [3 + 2]-cycloaddition between nonstabilized azomethyne ylide and endocyclic electron-deficient alkenes was elaborated. “Push–pull” alkenes and CF3-alkenes did not react with the azomethyne ylide under the previously reported conditions, and we de...

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Veröffentlicht in:	Journal of organic chemistry 2021-10, Vol.86 (19), p.13289-13309
Hauptverfasser:	Savych, Vladimir I, Mykhalchuk, Vladimir L, Melnychuk, Pavlo V, Isakov, Andrii O, Savchuk, Taras, Timoshenko, Vadim M, Siry, Sergiy A, Pavlenko, Sergiy O, Kovalenko, Dmytro V, Hryshchuk, Oleksandr V, Reznik, Vitalii A, Chalyk, Bohdan A, Yarmolchuk, Vladimir S, Rusanov, Eduard B, Mykhailiuk, Pavel K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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