Metabolic effects of high-intensity interval training and essential amino acids
High-intensity interval training (HIIT) promotes positive cardiometabolic and body composition changes. Essential amino acids (EAA) may support changes associated with HIIT, but evaluation of potential synergistic effects is lacking. The purpose of this study was to compare independent and combined...
Gespeichert in:
| Veröffentlicht in: | European journal of applied physiology 2021-12, Vol.121 (12), p.3297-3311 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 3311 |
|---|---|
| container_issue | 12 |
| container_start_page | 3297 |
| container_title | European journal of applied physiology |
| container_volume | 121 |
| creator | Hirsch, Katie R. Greenwalt, Casey E. Cabre, Hannah E. Gould, Lacey M. Brewer, Gabrielle J. Blue, Malia N. M. Ferrando, Arny A. Huffman, Kim M. Mayer-Davis, Elizabeth J. Ryan, Eric D. Smith-Ryan, Abbie E. |
| description | High-intensity interval training (HIIT) promotes positive cardiometabolic and body composition changes. Essential amino acids (EAA) may support changes associated with HIIT, but evaluation of potential synergistic effects is lacking. The purpose of this study was to compare independent and combined effects of HIIT and EAA on total body composition and metabolism in men and women considered overweight/obese; an exploratory aim was to evaluate the modulatory effects of sex. Sixty-six healthy adults (50% female; Age: 36.7 ± 6.0 years; BMI: 32.0 ± 4.2 kg/m
2
) completed 8 weeks of: (1) HIIT, 2 days/weeks; (2) EAA supplementation, 3.6 g twice daily; (3) HIIT + EAA; or (4) control. Body composition, resting metabolic rate (RMR), substrate metabolism (respiratory exchange ratio; RER), and cardiorespiratory fitness were measured at baseline, 4 weeks, and 8 weeks; cardiometabolic blood markers were measured at baseline and 8 weeks. Differences between groups were assessed by linear mixed models covaried for baseline values, followed by 95% confidence intervals (CI) on adjusted mean change scores. There were no significant changes in body composition (
p
> 0.05) for any group. Changes in RER, but not RMR, occurred with HIIT (mean change; [95% CI]: − 0.04; [− 0.07, − 0.02]) and EAA (− 0.03; [− 0.06, − 0.01]) after 8 weeks. Cardiorespiratory fitness increased following 8 weeks of HIIT (+ 5.1 ml/kg/min [3.3,6.8]) and HIIT + EAA (+ 4.1 ml/kg/min [1.0,6.4]). Changes with HIIT + EAA were not significantly different from HIIT. There were no changes in cardiometabolic markers (
p
> 0.05) and no sex interaction (
p
> 0.05). HIIT is efficacious for promoting positive changes in cardiorespiratory fitness and resting substrate metabolism in adults considered overweight/obese. Addition of EAA did not significantly enhance HIIT-induced adaptations. ClinicalTrials.gov ID#NCT04080102. |
| doi_str_mv | 10.1007/s00421-021-04792-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2564137564</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2593746781</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-4339a0c6814cd903a095b442d187b523bab7eb51a9b9f854197e0e917ccbc8eb3</originalsourceid><addsrcrecordid>eNp9kE1PwzAMhiMEYmPwBzigSly4FPLVpjmiiS8JtAucqyR1t0xdOpIWaf-eVB1D4sDBsmU_fm29CF0SfEswFncBY05JiofgQtKUH6Ep4UymOaPi-FATOUFnIawxxgUlxSmaMM6pEIxO0eINOqXbxpoE6hpMF5K2TlZ2uUqt68AF2-2SofJfqkk6r6yzbpkoVyUQArjOxrbaWNcmytgqnKOTWjUBLvZ5hj4eH97nz-nr4ullfv-aGiayLuWMSYVNXhBuKomZwjLT8amKFEJnlGmlBeiMKKllXWScSAEYJBHGaFOAZjN0M-puffvZQ-jKjQ0GmkY5aPtQ0iznJJ7KeUSv_6DrtvcufhcpyQTPRUEiRUfK-DYED3W59Xaj_K4kuBzsLke7SzzEYHc5SF_tpXu9geqw8uNvBNgIhDhyS_C_t_-R_QayO4oQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2593746781</pqid></control><display><type>article</type><title>Metabolic effects of high-intensity interval training and essential amino acids</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Hirsch, Katie R. ; Greenwalt, Casey E. ; Cabre, Hannah E. ; Gould, Lacey M. ; Brewer, Gabrielle J. ; Blue, Malia N. M. ; Ferrando, Arny A. ; Huffman, Kim M. ; Mayer-Davis, Elizabeth J. ; Ryan, Eric D. ; Smith-Ryan, Abbie E.</creator><creatorcontrib>Hirsch, Katie R. ; Greenwalt, Casey E. ; Cabre, Hannah E. ; Gould, Lacey M. ; Brewer, Gabrielle J. ; Blue, Malia N. M. ; Ferrando, Arny A. ; Huffman, Kim M. ; Mayer-Davis, Elizabeth J. ; Ryan, Eric D. ; Smith-Ryan, Abbie E.</creatorcontrib><description>High-intensity interval training (HIIT) promotes positive cardiometabolic and body composition changes. Essential amino acids (EAA) may support changes associated with HIIT, but evaluation of potential synergistic effects is lacking. The purpose of this study was to compare independent and combined effects of HIIT and EAA on total body composition and metabolism in men and women considered overweight/obese; an exploratory aim was to evaluate the modulatory effects of sex. Sixty-six healthy adults (50% female; Age: 36.7 ± 6.0 years; BMI: 32.0 ± 4.2 kg/m
2
) completed 8 weeks of: (1) HIIT, 2 days/weeks; (2) EAA supplementation, 3.6 g twice daily; (3) HIIT + EAA; or (4) control. Body composition, resting metabolic rate (RMR), substrate metabolism (respiratory exchange ratio; RER), and cardiorespiratory fitness were measured at baseline, 4 weeks, and 8 weeks; cardiometabolic blood markers were measured at baseline and 8 weeks. Differences between groups were assessed by linear mixed models covaried for baseline values, followed by 95% confidence intervals (CI) on adjusted mean change scores. There were no significant changes in body composition (
p
> 0.05) for any group. Changes in RER, but not RMR, occurred with HIIT (mean change; [95% CI]: − 0.04; [− 0.07, − 0.02]) and EAA (− 0.03; [− 0.06, − 0.01]) after 8 weeks. Cardiorespiratory fitness increased following 8 weeks of HIIT (+ 5.1 ml/kg/min [3.3,6.8]) and HIIT + EAA (+ 4.1 ml/kg/min [1.0,6.4]). Changes with HIIT + EAA were not significantly different from HIIT. There were no changes in cardiometabolic markers (
p
> 0.05) and no sex interaction (
p
> 0.05). HIIT is efficacious for promoting positive changes in cardiorespiratory fitness and resting substrate metabolism in adults considered overweight/obese. Addition of EAA did not significantly enhance HIIT-induced adaptations. ClinicalTrials.gov ID#NCT04080102.</description><identifier>ISSN: 1439-6319</identifier><identifier>EISSN: 1439-6327</identifier><identifier>DOI: 10.1007/s00421-021-04792-4</identifier><identifier>PMID: 34427732</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adaptation ; Adult ; Amino acids ; Amino Acids, Essential - administration & dosage ; Biomarkers - blood ; Biomedical and Life Sciences ; Biomedicine ; Body Composition ; Body Mass Index ; Body weight ; Cardiorespiratory Fitness ; Energy Metabolism ; Female ; High-Intensity Interval Training ; Human Physiology ; Humans ; Interval training ; Male ; Metabolic rate ; Metabolism ; Middle Aged ; NCT ; NCT04080102 ; Obesity - metabolism ; Occupational Medicine/Industrial Medicine ; Original Article ; Overweight ; Overweight - metabolism ; Respiration ; Sports Medicine ; Supplements</subject><ispartof>European journal of applied physiology, 2021-12, Vol.121 (12), p.3297-3311</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021. corrected publication 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021. corrected publication 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-4339a0c6814cd903a095b442d187b523bab7eb51a9b9f854197e0e917ccbc8eb3</citedby><cites>FETCH-LOGICAL-c375t-4339a0c6814cd903a095b442d187b523bab7eb51a9b9f854197e0e917ccbc8eb3</cites><orcidid>0000-0002-0899-0139</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00421-021-04792-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00421-021-04792-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34427732$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hirsch, Katie R.</creatorcontrib><creatorcontrib>Greenwalt, Casey E.</creatorcontrib><creatorcontrib>Cabre, Hannah E.</creatorcontrib><creatorcontrib>Gould, Lacey M.</creatorcontrib><creatorcontrib>Brewer, Gabrielle J.</creatorcontrib><creatorcontrib>Blue, Malia N. M.</creatorcontrib><creatorcontrib>Ferrando, Arny A.</creatorcontrib><creatorcontrib>Huffman, Kim M.</creatorcontrib><creatorcontrib>Mayer-Davis, Elizabeth J.</creatorcontrib><creatorcontrib>Ryan, Eric D.</creatorcontrib><creatorcontrib>Smith-Ryan, Abbie E.</creatorcontrib><title>Metabolic effects of high-intensity interval training and essential amino acids</title><title>European journal of applied physiology</title><addtitle>Eur J Appl Physiol</addtitle><addtitle>Eur J Appl Physiol</addtitle><description>High-intensity interval training (HIIT) promotes positive cardiometabolic and body composition changes. Essential amino acids (EAA) may support changes associated with HIIT, but evaluation of potential synergistic effects is lacking. The purpose of this study was to compare independent and combined effects of HIIT and EAA on total body composition and metabolism in men and women considered overweight/obese; an exploratory aim was to evaluate the modulatory effects of sex. Sixty-six healthy adults (50% female; Age: 36.7 ± 6.0 years; BMI: 32.0 ± 4.2 kg/m
2
) completed 8 weeks of: (1) HIIT, 2 days/weeks; (2) EAA supplementation, 3.6 g twice daily; (3) HIIT + EAA; or (4) control. Body composition, resting metabolic rate (RMR), substrate metabolism (respiratory exchange ratio; RER), and cardiorespiratory fitness were measured at baseline, 4 weeks, and 8 weeks; cardiometabolic blood markers were measured at baseline and 8 weeks. Differences between groups were assessed by linear mixed models covaried for baseline values, followed by 95% confidence intervals (CI) on adjusted mean change scores. There were no significant changes in body composition (
p
> 0.05) for any group. Changes in RER, but not RMR, occurred with HIIT (mean change; [95% CI]: − 0.04; [− 0.07, − 0.02]) and EAA (− 0.03; [− 0.06, − 0.01]) after 8 weeks. Cardiorespiratory fitness increased following 8 weeks of HIIT (+ 5.1 ml/kg/min [3.3,6.8]) and HIIT + EAA (+ 4.1 ml/kg/min [1.0,6.4]). Changes with HIIT + EAA were not significantly different from HIIT. There were no changes in cardiometabolic markers (
p
> 0.05) and no sex interaction (
p
> 0.05). HIIT is efficacious for promoting positive changes in cardiorespiratory fitness and resting substrate metabolism in adults considered overweight/obese. Addition of EAA did not significantly enhance HIIT-induced adaptations. ClinicalTrials.gov ID#NCT04080102.</description><subject>Adaptation</subject><subject>Adult</subject><subject>Amino acids</subject><subject>Amino Acids, Essential - administration & dosage</subject><subject>Biomarkers - blood</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Body Composition</subject><subject>Body Mass Index</subject><subject>Body weight</subject><subject>Cardiorespiratory Fitness</subject><subject>Energy Metabolism</subject><subject>Female</subject><subject>High-Intensity Interval Training</subject><subject>Human Physiology</subject><subject>Humans</subject><subject>Interval training</subject><subject>Male</subject><subject>Metabolic rate</subject><subject>Metabolism</subject><subject>Middle Aged</subject><subject>NCT</subject><subject>NCT04080102</subject><subject>Obesity - metabolism</subject><subject>Occupational Medicine/Industrial Medicine</subject><subject>Original Article</subject><subject>Overweight</subject><subject>Overweight - metabolism</subject><subject>Respiration</subject><subject>Sports Medicine</subject><subject>Supplements</subject><issn>1439-6319</issn><issn>1439-6327</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kE1PwzAMhiMEYmPwBzigSly4FPLVpjmiiS8JtAucqyR1t0xdOpIWaf-eVB1D4sDBsmU_fm29CF0SfEswFncBY05JiofgQtKUH6Ep4UymOaPi-FATOUFnIawxxgUlxSmaMM6pEIxO0eINOqXbxpoE6hpMF5K2TlZ2uUqt68AF2-2SofJfqkk6r6yzbpkoVyUQArjOxrbaWNcmytgqnKOTWjUBLvZ5hj4eH97nz-nr4ullfv-aGiayLuWMSYVNXhBuKomZwjLT8amKFEJnlGmlBeiMKKllXWScSAEYJBHGaFOAZjN0M-puffvZQ-jKjQ0GmkY5aPtQ0iznJJ7KeUSv_6DrtvcufhcpyQTPRUEiRUfK-DYED3W59Xaj_K4kuBzsLke7SzzEYHc5SF_tpXu9geqw8uNvBNgIhDhyS_C_t_-R_QayO4oQ</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Hirsch, Katie R.</creator><creator>Greenwalt, Casey E.</creator><creator>Cabre, Hannah E.</creator><creator>Gould, Lacey M.</creator><creator>Brewer, Gabrielle J.</creator><creator>Blue, Malia N. M.</creator><creator>Ferrando, Arny A.</creator><creator>Huffman, Kim M.</creator><creator>Mayer-Davis, Elizabeth J.</creator><creator>Ryan, Eric D.</creator><creator>Smith-Ryan, Abbie E.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-0899-0139</orcidid></search><sort><creationdate>20211201</creationdate><title>Metabolic effects of high-intensity interval training and essential amino acids</title><author>Hirsch, Katie R. ; Greenwalt, Casey E. ; Cabre, Hannah E. ; Gould, Lacey M. ; Brewer, Gabrielle J. ; Blue, Malia N. M. ; Ferrando, Arny A. ; Huffman, Kim M. ; Mayer-Davis, Elizabeth J. ; Ryan, Eric D. ; Smith-Ryan, Abbie E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-4339a0c6814cd903a095b442d187b523bab7eb51a9b9f854197e0e917ccbc8eb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adaptation</topic><topic>Adult</topic><topic>Amino acids</topic><topic>Amino Acids, Essential - administration & dosage</topic><topic>Biomarkers - blood</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Body Composition</topic><topic>Body Mass Index</topic><topic>Body weight</topic><topic>Cardiorespiratory Fitness</topic><topic>Energy Metabolism</topic><topic>Female</topic><topic>High-Intensity Interval Training</topic><topic>Human Physiology</topic><topic>Humans</topic><topic>Interval training</topic><topic>Male</topic><topic>Metabolic rate</topic><topic>Metabolism</topic><topic>Middle Aged</topic><topic>NCT</topic><topic>NCT04080102</topic><topic>Obesity - metabolism</topic><topic>Occupational Medicine/Industrial Medicine</topic><topic>Original Article</topic><topic>Overweight</topic><topic>Overweight - metabolism</topic><topic>Respiration</topic><topic>Sports Medicine</topic><topic>Supplements</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hirsch, Katie R.</creatorcontrib><creatorcontrib>Greenwalt, Casey E.</creatorcontrib><creatorcontrib>Cabre, Hannah E.</creatorcontrib><creatorcontrib>Gould, Lacey M.</creatorcontrib><creatorcontrib>Brewer, Gabrielle J.</creatorcontrib><creatorcontrib>Blue, Malia N. M.</creatorcontrib><creatorcontrib>Ferrando, Arny A.</creatorcontrib><creatorcontrib>Huffman, Kim M.</creatorcontrib><creatorcontrib>Mayer-Davis, Elizabeth J.</creatorcontrib><creatorcontrib>Ryan, Eric D.</creatorcontrib><creatorcontrib>Smith-Ryan, Abbie E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of applied physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hirsch, Katie R.</au><au>Greenwalt, Casey E.</au><au>Cabre, Hannah E.</au><au>Gould, Lacey M.</au><au>Brewer, Gabrielle J.</au><au>Blue, Malia N. M.</au><au>Ferrando, Arny A.</au><au>Huffman, Kim M.</au><au>Mayer-Davis, Elizabeth J.</au><au>Ryan, Eric D.</au><au>Smith-Ryan, Abbie E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolic effects of high-intensity interval training and essential amino acids</atitle><jtitle>European journal of applied physiology</jtitle><stitle>Eur J Appl Physiol</stitle><addtitle>Eur J Appl Physiol</addtitle><date>2021-12-01</date><risdate>2021</risdate><volume>121</volume><issue>12</issue><spage>3297</spage><epage>3311</epage><pages>3297-3311</pages><issn>1439-6319</issn><eissn>1439-6327</eissn><abstract>High-intensity interval training (HIIT) promotes positive cardiometabolic and body composition changes. Essential amino acids (EAA) may support changes associated with HIIT, but evaluation of potential synergistic effects is lacking. The purpose of this study was to compare independent and combined effects of HIIT and EAA on total body composition and metabolism in men and women considered overweight/obese; an exploratory aim was to evaluate the modulatory effects of sex. Sixty-six healthy adults (50% female; Age: 36.7 ± 6.0 years; BMI: 32.0 ± 4.2 kg/m
2
) completed 8 weeks of: (1) HIIT, 2 days/weeks; (2) EAA supplementation, 3.6 g twice daily; (3) HIIT + EAA; or (4) control. Body composition, resting metabolic rate (RMR), substrate metabolism (respiratory exchange ratio; RER), and cardiorespiratory fitness were measured at baseline, 4 weeks, and 8 weeks; cardiometabolic blood markers were measured at baseline and 8 weeks. Differences between groups were assessed by linear mixed models covaried for baseline values, followed by 95% confidence intervals (CI) on adjusted mean change scores. There were no significant changes in body composition (
p
> 0.05) for any group. Changes in RER, but not RMR, occurred with HIIT (mean change; [95% CI]: − 0.04; [− 0.07, − 0.02]) and EAA (− 0.03; [− 0.06, − 0.01]) after 8 weeks. Cardiorespiratory fitness increased following 8 weeks of HIIT (+ 5.1 ml/kg/min [3.3,6.8]) and HIIT + EAA (+ 4.1 ml/kg/min [1.0,6.4]). Changes with HIIT + EAA were not significantly different from HIIT. There were no changes in cardiometabolic markers (
p
> 0.05) and no sex interaction (
p
> 0.05). HIIT is efficacious for promoting positive changes in cardiorespiratory fitness and resting substrate metabolism in adults considered overweight/obese. Addition of EAA did not significantly enhance HIIT-induced adaptations. ClinicalTrials.gov ID#NCT04080102.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34427732</pmid><doi>10.1007/s00421-021-04792-4</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0002-0899-0139</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1439-6319 |
| ispartof | European journal of applied physiology, 2021-12, Vol.121 (12), p.3297-3311 |
| issn | 1439-6319 1439-6327 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2564137564 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adaptation Adult Amino acids Amino Acids, Essential - administration & dosage Biomarkers - blood Biomedical and Life Sciences Biomedicine Body Composition Body Mass Index Body weight Cardiorespiratory Fitness Energy Metabolism Female High-Intensity Interval Training Human Physiology Humans Interval training Male Metabolic rate Metabolism Middle Aged NCT NCT04080102 Obesity - metabolism Occupational Medicine/Industrial Medicine Original Article Overweight Overweight - metabolism Respiration Sports Medicine Supplements |
| title | Metabolic effects of high-intensity interval training and essential amino acids |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T23%3A37%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Metabolic%20effects%20of%20high-intensity%20interval%20training%20and%20essential%20amino%20acids&rft.jtitle=European%20journal%20of%20applied%20physiology&rft.au=Hirsch,%20Katie%20R.&rft.date=2021-12-01&rft.volume=121&rft.issue=12&rft.spage=3297&rft.epage=3311&rft.pages=3297-3311&rft.issn=1439-6319&rft.eissn=1439-6327&rft_id=info:doi/10.1007/s00421-021-04792-4&rft_dat=%3Cproquest_cross%3E2593746781%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2593746781&rft_id=info:pmid/34427732&rfr_iscdi=true |