Exfoliated bentonite/alginate nanocomposite hydrogel enhances intestinal delivery of probiotics by resistance to gastric pH and on-demand disintegration

In this study, we developed Lactobacillus rhamnosus GG (LGG)-encapsulating exfoliated bentonite/alginate nanocomposite hydrogels for protecting probiotics by delaying gastric fluid penetration into the nanocomposite and their on-demand release in the intestine. The pore size of the bentonite/alginat...

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Veröffentlicht in:	Carbohydrate polymers 2021-11, Vol.272, p.118462-118462, Article 118462
Hauptverfasser:	Kim, Jihyun, Hlaing, Shwe Phyu, Lee, Juho, Saparbayeva, Aruzhan, Kim, Sangsik, Hwang, Dong Soo, Lee, Eun Hee, Yoon, In-Soo, Yun, Hwayoung, Kim, Min-Soo, Moon, Hyung Ryong, Jung, Yunjin, Yoo, Jin-Wook
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Alginate Alginates - chemistry Animals Bentonite Bentonite - chemistry Feces - microbiology Gastric pH resistance Hydrogels - chemistry Hydrogen-Ion Concentration Intestinal delivery Intestines - metabolism Lactobacillus rhamnosus Male Mice Mice, Inbred ICR Microbial Viability Nanocomposite Nanocomposites - chemistry Probiotics Probiotics - administration & dosage Probiotics - chemistry Spectroscopy, Fourier Transform Infrared - methods X-Ray Diffraction - methods
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