Can hypoxia-inducible factor-1α overexpression discriminate human colorectal cancers with different microsatellite instability?

Clinicopathological features of high-frequency microsatellite instability (MSI-H) colorectal cancers (CRCs) are different from low-frequency MSI (MSI-L) and microsatellite stable (MSS) CRCs. The clinical features of MSI-L cases are unknown, and although the tumors usually show instability for dinucl...

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Veröffentlicht in:	Genes & Genetic Systems 2021/08/01, Vol.96(4), pp.193-198
Hauptverfasser:	Arabsorkhi, Zahra, Sadeghi, Hossein, Gharib, Ehsan, Rejali, Leili, Asadzadeh-Aghdaei, Hamid, Nazemalhosseini-Mojarad, Ehsan
Format:	Artikel
Sprache:	eng
Schlagworte:	colorectal cancer (CRC) Colorectal Neoplasms - genetics HIF-1α Humans Hypoxia-Inducible Factor 1, alpha Subunit - genetics Microsatellite Instability microsatellite instability (MSI) Microsatellite Repeats MSI-H MSI-L
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