A phase 2 study of anastrozole in patients with oestrogen receptor and/progesterone receptor positive recurrent/metastatic granulosa cell tumours/sex-cord stromal tumours of the ovary: The PARAGON/ANZGOG 0903 trial

Hormonal therapies are commonly prescribed to patients with metastatic granulosa cell tumours (GCT), based on high response rates in small retrospective studies. Aromatase inhibitors (AIs) are reported to have high response rates and an accepted treatment option. We report the results of a phase 2 t...

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Veröffentlicht in:	Gynecologic oncology 2021-10, Vol.163 (1), p.72-78
Hauptverfasser:	Banerjee, Susana N., Tang, Monica, O'Connell, Rachel L., Sjoquist, Katrin, Clamp, Andrew R., Millan, David, Nottley, Steven, Lord, Rosemary, Mullassery, Vinod Menon, Hall, Marcia, Gourley, Charlie, Bonaventura, Tony, Goh, Jeffrey C., Sykes, Peter, Grant, Peter T., McNally, Orla, Alexander, Laura, Kelly, Caroline, Carty, Karen, Divers, Laura, Bradshaw, N., Edmondson, Richard J., Friedlander, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anastrozole - therapeutic use Aromatase inhibitors Clinical benefit Female Granulosa Cell Tumor - chemistry Granulosa Cell Tumor - drug therapy Granulosa Cell Tumor - mortality Granulosa cell tumour ovary Humans Middle Aged Neoplasm Recurrence, Local - chemistry Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - mortality Ovarian Neoplasms - chemistry Ovarian Neoplasms - drug therapy Ovarian Neoplasms - mortality Quality of Life Receptors, Estrogen - analysis Receptors, Progesterone - analysis Response Sex Cord-Gonadal Stromal Tumors - chemistry Sex Cord-Gonadal Stromal Tumors - drug therapy Sex Cord-Gonadal Stromal Tumors - mortality
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