Therapeutic activity of a Salmonella-vectored Schistosoma mansoni vaccine in a mouse model of chronic infection

Schistosomiasis is an important fresh-water-borne parasitic disease caused by trematode worms of the genus Schistosoma. With > 250 million people infected worldwide and approximately 800 million people at risk, the World Health Organization considers schistosomiasis to be the most important human...

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Veröffentlicht in:	Vaccine 2021-09, Vol.39 (39), p.5580-5588
Hauptverfasser:	Hassan, Adam S., Perera, Dilhan J., Ward, Brian J., Ndao, Momar
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Cathepsin B Chemokines Chronic illnesses Chronic infection Cytokines Drug dosages Eggs Enzymes Immunization Immunoglobulin G Infections Lymphocytes T Morphology Murine challenge Parasites Parasitic diseases Praziquantel Salmonella Salmonella Typhimurium Schedules Schistosoma mansoni Schistosomiasis Splenocytes Therapeutic Tropical diseases Vaccine Vaccines Vectors Worms YS1646
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