Unexpected Coelenterazine Degradation Products of Beroe abyssicola Photoprotein Photoinactivation

Ca2+-regulated photoproteins of ctenophores lose bioluminescence activity when exposed to visible light. Little is known about the chemical nature of chromophore photoinactivation. Using a total synthesis strategy, we have established the structures of two unusual coelenterazine products, isolated f...

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Veröffentlicht in:	Organic letters 2021-09, Vol.23 (17), p.6846-6849
Hauptverfasser:	Burakova, Ludmila P, Lyakhovich, Maria S, Mineev, Konstantin S, Petushkov, Valentin N, Zagitova, Renata I, Tsarkova, Aleksandra S, Kovalchuk, Sergey I, Yampolsky, Ilia V, Vysotski, Eugene S, Kaskova, Zinaida M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - chemistry Calcium - metabolism Ctenophora - chemistry Imidazoles - chemistry Light Luminescent Proteins - chemistry Molecular Structure Pyrazines - chemistry
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