Diagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium

Restorative proctocolectomy with ileal pouch–anal anastomosis is an option for most patients with ulcerative colitis or familial adenomatous polyposis who require colectomy. Although the construction of an ileal pouch substantially improves patients' health-related quality of life, the surgery...

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Veröffentlicht in:The lancet. Gastroenterology & hepatology 2021-10, Vol.6 (10), p.826-849
Hauptverfasser: Shen, Bo, Kochhar, Gursimran S, Kariv, Revital, Liu, Xiuli, Navaneethan, Udayakumar, Rubin, David T, Cross, Raymond K, Sugita, Akira, D'Hoore, André, Schairer, Jason, Farraye, Francis A, Kiran, Ravi P, Fleshner, Philip, Rosh, Joel, Shah, Samir A, Chang, Shannon, Scherl, Ellen, Pardi, Darrell S, Schwartz, David A, Kotze, Paulo G, Bruining, David H, Kane, Sunanda V, Philpott, Jessica, Abraham, Bincy, Segal, Jonathan, Sedano, Rocio, Kayal, Maia, Bentley-Hibbert, Stuart, Tarabar, Dino, El-Hachem, Sandra, Sehgal, Priya, McCormick, James T, Picoraro, Joseph A, Silverberg, Mark S, Bernstein, Charles N, Sandborn, William J, Vermeire, Séverine
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container_end_page 849
container_issue 10
container_start_page 826
container_title The lancet. Gastroenterology & hepatology
container_volume 6
creator Shen, Bo
Kochhar, Gursimran S
Kariv, Revital
Liu, Xiuli
Navaneethan, Udayakumar
Rubin, David T
Cross, Raymond K
Sugita, Akira
D'Hoore, André
Schairer, Jason
Farraye, Francis A
Kiran, Ravi P
Fleshner, Philip
Rosh, Joel
Shah, Samir A
Chang, Shannon
Scherl, Ellen
Pardi, Darrell S
Schwartz, David A
Kotze, Paulo G
Bruining, David H
Kane, Sunanda V
Philpott, Jessica
Abraham, Bincy
Segal, Jonathan
Sedano, Rocio
Kayal, Maia
Bentley-Hibbert, Stuart
Tarabar, Dino
El-Hachem, Sandra
Sehgal, Priya
McCormick, James T
Picoraro, Joseph A
Silverberg, Mark S
Bernstein, Charles N
Sandborn, William J
Vermeire, Séverine
description Restorative proctocolectomy with ileal pouch–anal anastomosis is an option for most patients with ulcerative colitis or familial adenomatous polyposis who require colectomy. Although the construction of an ileal pouch substantially improves patients' health-related quality of life, the surgery is, directly or indirectly, associated with various structural, inflammatory, and functional adverse sequelae. Furthermore, the surgical procedure does not completely abolish the risk for neoplasia. Patients with ileal pouches often present with extraintestinal, systemic inflammatory conditions. The International Ileal Pouch Consortium was established to create this consensus document on the diagnosis and classification of ileal pouch disorders using available evidence and the panellists' expertise. In a given individual, the condition of the pouch can change over time. Therefore, close monitoring of the activity and progression of the disease is essential to make accurate modifications in the diagnosis and classification in a timely manner.
doi_str_mv 10.1016/S2468-1253(21)00101-1
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