Motopsin deficiency imparts partial insensitivity to doxorubicin-induced hippocampal impairments in adult mice

•Doxorubicin (Dox) decreased locomotion in wild-type (WT) and motopsin KO mice.•Dox disturbed the novel object recognition in WT mice, but not motopsin KO mice.•Dox increased parvalbumin neurons in WT mice, but not in motopsin KO mice.•Motopsin deficiency may raise insensitivity to chemobrain.•Resul...

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