A Retrospective Study of Psychotropic Drug Use and Prescription Opioid Initiation Among Older Adults

Individuals with mental health problems may be more vulnerable to using prescription opioids than their counterparts. Therefore, the main objective of this study was to assess the initiation of prescription opioids in older adults who used psychotropic drugs compared with those who did not. The auth...

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Veröffentlicht in:Population health management 2022-02, Vol.25 (1), p.126-133
Hauptverfasser: Khan, Shivani R, Heller, Debra A, Latty, Leroy L, LaSure, Michelle, Brown, Theresa V
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container_end_page 133
container_issue 1
container_start_page 126
container_title Population health management
container_volume 25
creator Khan, Shivani R
Heller, Debra A
Latty, Leroy L
LaSure, Michelle
Brown, Theresa V
description Individuals with mental health problems may be more vulnerable to using prescription opioids than their counterparts. Therefore, the main objective of this study was to assess the initiation of prescription opioids in older adults who used psychotropic drugs compared with those who did not. The authors used a retrospective cohort design and included a sample of older adults enrolled in Pennsylvania's Pharmaceutical Assistance Contract for the Elderly program who did not use prescription opioids in 2013. Using pharmacy claims, patients who used anxiolytics/sedatives/hypnotics (n = 13,512) or antidepressants (n = 17,492) between October and December 2013 were identified and compared with those who did not use anxiolytics/sedatives/hypnotics (n = 114,091) or antidepressants (n = 110,111) during that period, to determine the incidence of prescription opioid use in 2014. Chi-square tests and multivariate logistic regressions were performed for analyses. Compared with patients who did not use anxiolytics/sedatives/hypnotics, those who used were more likely to initiate prescription opioids (15.0% versus 22.0%, P  
doi_str_mv 10.1089/pop.2021.0129
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Compared with patients who did not use anxiolytics/sedatives/hypnotics, those who used were more likely to initiate prescription opioids (15.0% versus 22.0%, P  &lt; .0001). Similarly, compared with patients who did not use antidepressants, those who used were more likely to initiate prescription opioids (14.7% versus 21.9%, P  &lt; .0001). Multivariate logistic regression indicated that the odds of prescription opioid initiation increased with anxiolytic/sedative/hypnotic use by 44% (AOR = 1.44; P  &lt; .0001) and antidepressant use by 48% (AOR = 1.48; P  &lt; .0001) among older adults after adjusting for potential confounding variables. Results showed that prescription opioid initiation is associated with prior anxiolytic/sedative/hypnotic or antidepressant use among older adults. 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title A Retrospective Study of Psychotropic Drug Use and Prescription Opioid Initiation Among Older Adults
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