Nature and Dimensions of Systemic Hyperinflammation and its Attenuation by Convalescent Plasma in Severe COVID-19

Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19), has led to significant morbidity and mortality. While most suffer from mild symptoms, some patients progress to severe disease with acute respiratory distress syndrome (ARDS...

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Veröffentlicht in:	The Journal of infectious diseases 2021-08, Vol.224 (4), p.565-574
Hauptverfasser:	Bandopadhyay, Purbita, D’Rozario, Ranit, Lahiri, Abhishake, Sarif, Jafar, Ray, Yogiraj, Paul, Shekhar Ranjan, Roy, Rammohan, Maiti, Rajshekhar, Chaudhuri, Kausik, Bagchi, Saugata, Maiti, Ayan, Perwez, Mohammed Masoom, Sarkar, Biswanath Sharma, Roy, Devlina, Chakraborty, Rahul, Vasudevan, Janani Srinivasa, Sharma, Sachin, Biswas, Durba, Maiti, Chikam, Saha, Bibhuti, Bhattacharya, Prasun, Pandey, Rajesh, Chatterjee, Shilpak, Paul, Sandip, Ganguly, Dipyaman
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Inflammatory Agents - therapeutic use Antibodies, Neutralizing - immunology Coronaviruses COVID-19 COVID-19 - epidemiology COVID-19 - immunology COVID-19 - therapy COVID-19 - virology COVID-19 Drug Treatment COVID-19 Serotherapy Cytokines Cytokines - blood Cytokines - immunology Female Humans Hypoxia Immunization, Passive - methods India - epidemiology Inflammation Interleukin 6 Male Middle Aged Morbidity Patients Plasma Respiratory distress syndrome Respiratory Distress Syndrome - drug therapy Respiratory Distress Syndrome - immunology RNA, Viral - isolation & purification SARS-CoV-2 - immunology SARS-CoV-2 - isolation & purification Severe acute respiratory syndrome coronavirus 2 Viral Load γ-Interferon
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