Organocatalytic Asymmetric Dearomatization Reaction for the Synthesis of Axial Chiral Allene-Derived Naphthalenones Bearing Quaternary Stereocenters

The highly regio-, diastereo-, and enantioselective dearomatization reaction of 1-substituted 2-naphthols and β,γ-alkynyl-α-imino esters with complete atom economy is disclosed via chiral phosphoric acid catalysis. This protocol provides facile and efficient access to asymmetric construction of a br...

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Veröffentlicht in:	Organic letters 2021-09, Vol.23 (17), p.6606-6611
Hauptverfasser:	Woldegiorgis, Alemayehu Gashaw, Han, Zhao, Lin, Xufeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry, Organic Physical Sciences Science & Technology
Online-Zugang:	Volltext
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