Effect of maternal apical periodontitis on the final step of insulin signalling and inflammatory pathway in the adult male offspring of rats

Aim To evaluate the final step of insulin signalling, inflammatory pathway (related to the inhibition of insulin signalling), peroxisome proliferator‐activated receptor‐gamma coactivator 1α (PGC‐1α) protein content and DNA methylation in the Slc2a4 gene promoter region in the skeletal muscle of adul...

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Veröffentlicht in:	International endodontic journal 2021-11, Vol.54 (11), p.2113-2124
Hauptverfasser:	Tsosura, Thaís Verônica Saori, Mattera, Maria Sara de Lima Coutinho, Chiba, Fernando Yamamoto, Carnevali, Ana Carolina Nascimento, Belardi, Bianca Elvira, Santos, Rodrigo Martins, Cintra, Luciano Tavares Angelo, Lopes, Flávia Lombardi, Scaramele, Natália Francisco, Matsushita, Doris Hissako
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein apical periodontitis Dentistry Deoxyribonucleic acid DNA DNA methylation foetal development Gastrocnemius muscle Gene expression glucose transporter type 4 GLUT4 gene Gum disease Inflammation Insulin Kinases Offspring Periodontitis Phosphorylation Polymerase chain reaction Proteins Rodents Serine Signal transduction Skeletal muscle Statistical analysis Teeth Threonine Tumor necrosis factor Western blotting
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