Can red blood cell distribution width (RDW) level predict the severity of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)?
Background Elevated red blood cell distribution width (RDW) levels were associated with mortality in patients with stable chronic obstructive lung pulmonary diseases (COPD). There are limited data about RDW levels in acute exacerbation of COPD (AECOPD). Aim/Objective The association of the RDW level...
Gespeichert in:
| Veröffentlicht in: | International journal of clinical practice (Esher) 2021-11, Vol.75 (11), p.e14730-n/a |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | n/a |
|---|---|
| container_issue | 11 |
| container_start_page | e14730 |
| container_title | International journal of clinical practice (Esher) |
| container_volume | 75 |
| creator | Alparslan Bekir, Sumeyye Tuncay, Eylem Gungor, Sinem Yalcinsoy, Murat Sogukpinar, Özlem Gundogus, Baran Aksoy, Emine Agca, Meltem Agca Altunbey, Sinem Turker, Hatice Karakurt, Zuhal |
| description | Background
Elevated red blood cell distribution width (RDW) levels were associated with mortality in patients with stable chronic obstructive lung pulmonary diseases (COPD). There are limited data about RDW levels in acute exacerbation of COPD (AECOPD).
Aim/Objective
The association of the RDW levels with the severity of AECOPD was evaluated according to admission location, (outpatient‐clinic, ward and intensive care unit (ICU)).
Methods
Cross sectional retrospective study was designed in tertiary care hospital for chest diseases in 2015. Previously COPD diagnosed patients admitted to hospital outpatient‐clinic, ward and ICU due to AECOPD were included in the study. Patients demographics, RDW, biomarkers (CRP, RDW, Neutrophil to lymphocyte ratio (NLR), platelet to mean platelet volume (PLT‐MPV)) C‐CRP, biochemistry values were recorded from hospital electronic system. RDW values were subdivided below 0.11% (low), above and equal 0.15% (high) and between 0.11%‐0.15% (normal). Neutrophil to lymphocyte ratio (NLR) and platelet to mean platelet volume (PLT‐MPV) were also calculated. Biomarker values were compared according to where AECOPD was treated.
Results
2771 COPD patients (33% female) and 1429 outpatients‐clinic, 1156 ward and 186 ICU were enrolled in the study. The median RDW values in outpatients‐clinic, ward and ICU were 0.16 (0.09‐0.26), 0.07 (0.01‐0.14) and 0.01 (0.00‐0.07) respectively (P |
| doi_str_mv | 10.1111/ijcp.14730 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2560833084</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2583417135</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3340-1fc6b7e05f9b86ec056cbd005919d45b9c4f100cc3dfc1e11947eb416c340fe93</originalsourceid><addsrcrecordid>eNp9kU1r3DAQhk1poWmaS3-BoJdNwKlmJfnjVILzWRYSQkKOxhqPWS1ey5XkTfZX5C9Hm82ph85lhuF554M3SX4AP4UYv8wKx1OQueCfkgPI5TyFuYTPsRZZkSou4GvyzfsV53OlCn6QvFbNwBy1TPfWtgyp71lrfHBGT8HYgT2bNizZ7P786Zj1tKGejRE3GFhYEvOx40zYMtuxBqdAjF4aJKebd3Hs4tLZwSCzOg6dMJgNsXHq13Zo3Ha3ihpPbHZ2Ud3enR___p586Zre09FHPkweLy8equt0cXt1U50tUhRC8hQ6zHROXHWlLjJCrjLULeeqhLKVSpcoO-AcUbQdAgGUMictIcOo7qgUh8lsP3d09u9EPtRr43ffNwPZyddzlfFCCF7IiP78B13ZyQ3xukgVQkIOQkXqZE-hs9476urRmXX8sQZe77ypd97U795EGPbws-lp-x-yvvlT3e01b5Fzkes</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2583417135</pqid></control><display><type>article</type><title>Can red blood cell distribution width (RDW) level predict the severity of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)?</title><source>Wiley-Blackwell Journals</source><creator>Alparslan Bekir, Sumeyye ; Tuncay, Eylem ; Gungor, Sinem ; Yalcinsoy, Murat ; Sogukpinar, Özlem ; Gundogus, Baran ; Aksoy, Emine ; Agca, Meltem ; Agca Altunbey, Sinem ; Turker, Hatice ; Karakurt, Zuhal</creator><creatorcontrib>Alparslan Bekir, Sumeyye ; Tuncay, Eylem ; Gungor, Sinem ; Yalcinsoy, Murat ; Sogukpinar, Özlem ; Gundogus, Baran ; Aksoy, Emine ; Agca, Meltem ; Agca Altunbey, Sinem ; Turker, Hatice ; Karakurt, Zuhal</creatorcontrib><description>Background
Elevated red blood cell distribution width (RDW) levels were associated with mortality in patients with stable chronic obstructive lung pulmonary diseases (COPD). There are limited data about RDW levels in acute exacerbation of COPD (AECOPD).
Aim/Objective
The association of the RDW levels with the severity of AECOPD was evaluated according to admission location, (outpatient‐clinic, ward and intensive care unit (ICU)).
Methods
Cross sectional retrospective study was designed in tertiary care hospital for chest diseases in 2015. Previously COPD diagnosed patients admitted to hospital outpatient‐clinic, ward and ICU due to AECOPD were included in the study. Patients demographics, RDW, biomarkers (CRP, RDW, Neutrophil to lymphocyte ratio (NLR), platelet to mean platelet volume (PLT‐MPV)) C‐CRP, biochemistry values were recorded from hospital electronic system. RDW values were subdivided below 0.11% (low), above and equal 0.15% (high) and between 0.11%‐0.15% (normal). Neutrophil to lymphocyte ratio (NLR) and platelet to mean platelet volume (PLT‐MPV) were also calculated. Biomarker values were compared according to where AECOPD was treated.
Results
2771 COPD patients (33% female) and 1429 outpatients‐clinic, 1156 ward and 186 ICU were enrolled in the study. The median RDW values in outpatients‐clinic, ward and ICU were 0.16 (0.09‐0.26), 0.07 (0.01‐0.14) and 0.01 (0.00‐0.07) respectively (P < .001). In outpatient to ward and ICU, low RDW values were significantly increased (31%, 66%, 83%, respectively) and high RDW values significantly decreased (54%, 24%, 10%) (P < .001). According to attack severity, low RDW values were determined.
Conclusion
Patients with AECOPD, lower RDW values should be considered carefully. Lower RDW can be used for decision of COPD exacerbation severity and follow up treatment response</description><identifier>ISSN: 1368-5031</identifier><identifier>EISSN: 1742-1241</identifier><identifier>DOI: 10.1111/ijcp.14730</identifier><language>eng</language><publisher>London: Hindawi Limited</publisher><subject>Biomarkers ; Blood platelets ; Chronic obstructive pulmonary disease ; Demography ; Erythrocytes ; Leukocytes (neutrophilic) ; Lung diseases ; Lymphocytes ; Neutrophils ; Obstructive lung disease ; Patients ; Platelets</subject><ispartof>International journal of clinical practice (Esher), 2021-11, Vol.75 (11), p.e14730-n/a</ispartof><rights>2021 John Wiley & Sons Ltd</rights><rights>Copyright © 2021 John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3340-1fc6b7e05f9b86ec056cbd005919d45b9c4f100cc3dfc1e11947eb416c340fe93</citedby><cites>FETCH-LOGICAL-c3340-1fc6b7e05f9b86ec056cbd005919d45b9c4f100cc3dfc1e11947eb416c340fe93</cites><orcidid>0000-0002-3542-8133</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fijcp.14730$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fijcp.14730$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids></links><search><creatorcontrib>Alparslan Bekir, Sumeyye</creatorcontrib><creatorcontrib>Tuncay, Eylem</creatorcontrib><creatorcontrib>Gungor, Sinem</creatorcontrib><creatorcontrib>Yalcinsoy, Murat</creatorcontrib><creatorcontrib>Sogukpinar, Özlem</creatorcontrib><creatorcontrib>Gundogus, Baran</creatorcontrib><creatorcontrib>Aksoy, Emine</creatorcontrib><creatorcontrib>Agca, Meltem</creatorcontrib><creatorcontrib>Agca Altunbey, Sinem</creatorcontrib><creatorcontrib>Turker, Hatice</creatorcontrib><creatorcontrib>Karakurt, Zuhal</creatorcontrib><title>Can red blood cell distribution width (RDW) level predict the severity of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)?</title><title>International journal of clinical practice (Esher)</title><description>Background
Elevated red blood cell distribution width (RDW) levels were associated with mortality in patients with stable chronic obstructive lung pulmonary diseases (COPD). There are limited data about RDW levels in acute exacerbation of COPD (AECOPD).
Aim/Objective
The association of the RDW levels with the severity of AECOPD was evaluated according to admission location, (outpatient‐clinic, ward and intensive care unit (ICU)).
Methods
Cross sectional retrospective study was designed in tertiary care hospital for chest diseases in 2015. Previously COPD diagnosed patients admitted to hospital outpatient‐clinic, ward and ICU due to AECOPD were included in the study. Patients demographics, RDW, biomarkers (CRP, RDW, Neutrophil to lymphocyte ratio (NLR), platelet to mean platelet volume (PLT‐MPV)) C‐CRP, biochemistry values were recorded from hospital electronic system. RDW values were subdivided below 0.11% (low), above and equal 0.15% (high) and between 0.11%‐0.15% (normal). Neutrophil to lymphocyte ratio (NLR) and platelet to mean platelet volume (PLT‐MPV) were also calculated. Biomarker values were compared according to where AECOPD was treated.
Results
2771 COPD patients (33% female) and 1429 outpatients‐clinic, 1156 ward and 186 ICU were enrolled in the study. The median RDW values in outpatients‐clinic, ward and ICU were 0.16 (0.09‐0.26), 0.07 (0.01‐0.14) and 0.01 (0.00‐0.07) respectively (P < .001). In outpatient to ward and ICU, low RDW values were significantly increased (31%, 66%, 83%, respectively) and high RDW values significantly decreased (54%, 24%, 10%) (P < .001). According to attack severity, low RDW values were determined.
Conclusion
Patients with AECOPD, lower RDW values should be considered carefully. Lower RDW can be used for decision of COPD exacerbation severity and follow up treatment response</description><subject>Biomarkers</subject><subject>Blood platelets</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Demography</subject><subject>Erythrocytes</subject><subject>Leukocytes (neutrophilic)</subject><subject>Lung diseases</subject><subject>Lymphocytes</subject><subject>Neutrophils</subject><subject>Obstructive lung disease</subject><subject>Patients</subject><subject>Platelets</subject><issn>1368-5031</issn><issn>1742-1241</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kU1r3DAQhk1poWmaS3-BoJdNwKlmJfnjVILzWRYSQkKOxhqPWS1ey5XkTfZX5C9Hm82ph85lhuF554M3SX4AP4UYv8wKx1OQueCfkgPI5TyFuYTPsRZZkSou4GvyzfsV53OlCn6QvFbNwBy1TPfWtgyp71lrfHBGT8HYgT2bNizZ7P786Zj1tKGejRE3GFhYEvOx40zYMtuxBqdAjF4aJKebd3Hs4tLZwSCzOg6dMJgNsXHq13Zo3Ha3ihpPbHZ2Ud3enR___p586Zre09FHPkweLy8equt0cXt1U50tUhRC8hQ6zHROXHWlLjJCrjLULeeqhLKVSpcoO-AcUbQdAgGUMictIcOo7qgUh8lsP3d09u9EPtRr43ffNwPZyddzlfFCCF7IiP78B13ZyQ3xukgVQkIOQkXqZE-hs9476urRmXX8sQZe77ypd97U795EGPbws-lp-x-yvvlT3e01b5Fzkes</recordid><startdate>202111</startdate><enddate>202111</enddate><creator>Alparslan Bekir, Sumeyye</creator><creator>Tuncay, Eylem</creator><creator>Gungor, Sinem</creator><creator>Yalcinsoy, Murat</creator><creator>Sogukpinar, Özlem</creator><creator>Gundogus, Baran</creator><creator>Aksoy, Emine</creator><creator>Agca, Meltem</creator><creator>Agca Altunbey, Sinem</creator><creator>Turker, Hatice</creator><creator>Karakurt, Zuhal</creator><general>Hindawi Limited</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T5</scope><scope>7TK</scope><scope>7TS</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3542-8133</orcidid></search><sort><creationdate>202111</creationdate><title>Can red blood cell distribution width (RDW) level predict the severity of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)?</title><author>Alparslan Bekir, Sumeyye ; Tuncay, Eylem ; Gungor, Sinem ; Yalcinsoy, Murat ; Sogukpinar, Özlem ; Gundogus, Baran ; Aksoy, Emine ; Agca, Meltem ; Agca Altunbey, Sinem ; Turker, Hatice ; Karakurt, Zuhal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3340-1fc6b7e05f9b86ec056cbd005919d45b9c4f100cc3dfc1e11947eb416c340fe93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Biomarkers</topic><topic>Blood platelets</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Demography</topic><topic>Erythrocytes</topic><topic>Leukocytes (neutrophilic)</topic><topic>Lung diseases</topic><topic>Lymphocytes</topic><topic>Neutrophils</topic><topic>Obstructive lung disease</topic><topic>Patients</topic><topic>Platelets</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alparslan Bekir, Sumeyye</creatorcontrib><creatorcontrib>Tuncay, Eylem</creatorcontrib><creatorcontrib>Gungor, Sinem</creatorcontrib><creatorcontrib>Yalcinsoy, Murat</creatorcontrib><creatorcontrib>Sogukpinar, Özlem</creatorcontrib><creatorcontrib>Gundogus, Baran</creatorcontrib><creatorcontrib>Aksoy, Emine</creatorcontrib><creatorcontrib>Agca, Meltem</creatorcontrib><creatorcontrib>Agca Altunbey, Sinem</creatorcontrib><creatorcontrib>Turker, Hatice</creatorcontrib><creatorcontrib>Karakurt, Zuhal</creatorcontrib><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of clinical practice (Esher)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alparslan Bekir, Sumeyye</au><au>Tuncay, Eylem</au><au>Gungor, Sinem</au><au>Yalcinsoy, Murat</au><au>Sogukpinar, Özlem</au><au>Gundogus, Baran</au><au>Aksoy, Emine</au><au>Agca, Meltem</au><au>Agca Altunbey, Sinem</au><au>Turker, Hatice</au><au>Karakurt, Zuhal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Can red blood cell distribution width (RDW) level predict the severity of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)?</atitle><jtitle>International journal of clinical practice (Esher)</jtitle><date>2021-11</date><risdate>2021</risdate><volume>75</volume><issue>11</issue><spage>e14730</spage><epage>n/a</epage><pages>e14730-n/a</pages><issn>1368-5031</issn><eissn>1742-1241</eissn><abstract>Background
Elevated red blood cell distribution width (RDW) levels were associated with mortality in patients with stable chronic obstructive lung pulmonary diseases (COPD). There are limited data about RDW levels in acute exacerbation of COPD (AECOPD).
Aim/Objective
The association of the RDW levels with the severity of AECOPD was evaluated according to admission location, (outpatient‐clinic, ward and intensive care unit (ICU)).
Methods
Cross sectional retrospective study was designed in tertiary care hospital for chest diseases in 2015. Previously COPD diagnosed patients admitted to hospital outpatient‐clinic, ward and ICU due to AECOPD were included in the study. Patients demographics, RDW, biomarkers (CRP, RDW, Neutrophil to lymphocyte ratio (NLR), platelet to mean platelet volume (PLT‐MPV)) C‐CRP, biochemistry values were recorded from hospital electronic system. RDW values were subdivided below 0.11% (low), above and equal 0.15% (high) and between 0.11%‐0.15% (normal). Neutrophil to lymphocyte ratio (NLR) and platelet to mean platelet volume (PLT‐MPV) were also calculated. Biomarker values were compared according to where AECOPD was treated.
Results
2771 COPD patients (33% female) and 1429 outpatients‐clinic, 1156 ward and 186 ICU were enrolled in the study. The median RDW values in outpatients‐clinic, ward and ICU were 0.16 (0.09‐0.26), 0.07 (0.01‐0.14) and 0.01 (0.00‐0.07) respectively (P < .001). In outpatient to ward and ICU, low RDW values were significantly increased (31%, 66%, 83%, respectively) and high RDW values significantly decreased (54%, 24%, 10%) (P < .001). According to attack severity, low RDW values were determined.
Conclusion
Patients with AECOPD, lower RDW values should be considered carefully. Lower RDW can be used for decision of COPD exacerbation severity and follow up treatment response</abstract><cop>London</cop><pub>Hindawi Limited</pub><doi>10.1111/ijcp.14730</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-3542-8133</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1368-5031 |
| ispartof | International journal of clinical practice (Esher), 2021-11, Vol.75 (11), p.e14730-n/a |
| issn | 1368-5031 1742-1241 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2560833084 |
| source | Wiley-Blackwell Journals |
| subjects | Biomarkers Blood platelets Chronic obstructive pulmonary disease Demography Erythrocytes Leukocytes (neutrophilic) Lung diseases Lymphocytes Neutrophils Obstructive lung disease Patients Platelets |
| title | Can red blood cell distribution width (RDW) level predict the severity of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T06%3A34%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Can%20red%20blood%20cell%20distribution%20width%20(RDW)%20level%20predict%20the%20severity%20of%20acute%20exacerbation%20of%20chronic%20obstructive%20pulmonary%20disease%20(AECOPD)?&rft.jtitle=International%20journal%20of%20clinical%20practice%20(Esher)&rft.au=Alparslan%20Bekir,%20Sumeyye&rft.date=2021-11&rft.volume=75&rft.issue=11&rft.spage=e14730&rft.epage=n/a&rft.pages=e14730-n/a&rft.issn=1368-5031&rft.eissn=1742-1241&rft_id=info:doi/10.1111/ijcp.14730&rft_dat=%3Cproquest_cross%3E2583417135%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2583417135&rft_id=info:pmid/&rfr_iscdi=true |