Remodeling of Tumor Microenvironment by Tumor‐Targeting Nanozymes Enhances Immune Activation of CAR T Cells for Combination Therapy

Targeting B7‐H3 chimeric antigen receptor (CAR) T cells has antitumor potential for therapy of non‐small cell lung cancer (NSCLC) in preclinical studies. However, CAR T cell therapy remains a formidable challenge for the treatment of solid tumors due to the heterogeneous and immunosuppressive tumor...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2021-10, Vol.17 (43), p.e2102624-n/a
Hauptverfasser:	Zhu, Lipeng, Liu, Jie, Zhou, Guangyu, Liu, Tzu‐Ming, Dai, Yunlu, Nie, Guangjun, Zhao, Qi
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Anticancer properties Antigens B7‐H3 immune checkpoint chimeric antigen receptor T cell Immunosuppression immunotherapy Lymphocytes Nanotechnology nanozyme photothermal‐nanocatalytic effect Therapy Tumors
Online-Zugang:	Volltext
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