Long‐term chronological changes in renal function and functional renal volume after nephron‐sparing surgery: A prospective observational study

Objectives To investigate long‐term chronological changes in functional renal volume and renal function after nephron‐sparing surgery, and factors that contribute to the progression of postoperative chronic kidney disease. Methods A total of 80 patients who underwent nephron‐sparing surgery were enrolled in this prospective observational study. The renal function deterioration group was defined as patients whose estimated glomerular filtration rate at 5 postoperative years decreased by ≥20% relative to that before surgery. Results The predicted estimated glomerular filtration rate, calculated based on the functional renal volume at 5 postoperative years, was strongly correlated with the postoperative estimated glomerular filtration rate (Spearman’s ρ = 0.89, P