Human oocyte meiotic maturation is associated with a specific profile of alternatively spliced transcript isoforms

The transition from a transcriptionally active state (GV) to a transcriptionally inactive state (mature MII oocytes) is required for the acquisition of oocyte developmental competence. We hypothesize that the expression of specific genes at the in vivo matured (MII) stage could be modulated by postt...

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Veröffentlicht in:	Molecular reproduction and development 2021-09, Vol.88 (9), p.605-617
Hauptverfasser:	Cornet‐Bartolomé, David, Barragán, Montserrat, Zambelli, Filippo, Ferrer‐Vaquer, Anna, Tiscornia, Gustavo, Balcells, Susanna, Rodriguez, Amelia, Grinberg, Daniel, Vassena, Rita
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative splicing antral follicular count developmental competence DNA microarrays Gene expression Gene regulation human oocyte Isoforms Maturation Meiosis Mitochondria Oocytes Polymerase chain reaction Post-transcription
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