Synergistic antimicrobial activities of epigallocatechin gallate, myricetin, daidzein, gallic acid, epicatechin, 3‐hydroxy‐6‐methoxyflavone and genistein combined with antibiotics against ESKAPE pathogens

Aim To verify synergistic effects, we investigated the antimicrobial activity of seven phenolic phytochemicals (gallic acid; epicatechin; epigallocatechin gallate; daidzein; genistein; myricetin; 3‐hydroxy‐6‐methoxyflavone) in combination with six antibiotics against multidrug‐resistant isolates fro...

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Veröffentlicht in:	Journal of applied microbiology 2022-02, Vol.132 (2), p.949-963
Hauptverfasser:	Buchmann, David, Schultze, Nadin, Borchardt, Julia, Böttcher, Inken, Schaufler, Katharina, Guenther, Sebastian
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumannii Antagonism Anti-Bacterial Agents - pharmacology Antibiotics Antiinfectives and antibacterials Antimicrobial activity Antimicrobial agents Bacteria Catechin - analogs & derivatives Catechin - pharmacology checkerboard combination with antibiotic Daidzein Drug Resistance, Multiple, Bacterial Drug Synergism Epicatechin Epigallocatechin gallate ESKAPE strain Flavones Flavonoids Gallic acid Gallic Acid - pharmacology Genistein Genistein - pharmacology Isoflavones Microbial Sensitivity Tests natural products Pathogens Phenols Phytochemicals Synergistic effect
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