NetAUC: A network-based multi-biomarker identification method by AUC optimization

•Propose a novel method for identifying biomarkers by AUC optimization model.•Combine gene expression and topological information from protein-protein interaction network to construct the integrated network.•Introduce the label propagation algorithm to highlight the important genes.•Introduce the sm...

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Veröffentlicht in:	Methods (San Diego, Calif.) Calif.), 2022-02, Vol.198, p.56-64
Hauptverfasser:	Li, Xing-Yi, Xiang, Ju, Wu, Fang-Xiang, Li, Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Area Under Curve AUC optimization Biomarker Biomarkers Breast Neoplasms - diagnosis Breast Neoplasms - genetics Complex diseases Feature selection Female Humans Network information ROC Curve
Online-Zugang:	Volltext
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