Trajectories of kidney function in diabetes: a clinicopathological update

Diabetic nephropathy has been traditionally diagnosed based on persistently high albuminuria and a subsequent decline in glomerular filtration rate (GFR), which is widely recognized as the classical phenotype of diabetic kidney disease (DKD). Several studies have emphasized that trajectories of kidn...

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Veröffentlicht in:	Nature reviews. Nephrology 2021-11, Vol.17 (11), p.740-750
Hauptverfasser:	Oshima, Megumi, Shimizu, Miho, Yamanouchi, Masayuki, Toyama, Tadashi, Hara, Akinori, Furuichi, Kengo, Wada, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	692/163/2743/137/138 692/308/174 692/4022/1585/2759/1419 692/53/2422 Albuminuria - etiology Albuminuria - metabolism Albuminuria - pathology Albuminuria - physiopathology Antihypertensives Biopsy Blood pressure Care and treatment Development and progression Diabetes Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - metabolism Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - metabolism Diabetic nephropathies Diabetic Nephropathies - etiology Diabetic Nephropathies - metabolism Diabetic Nephropathies - pathology Diabetic Nephropathies - physiopathology Diabetic nephropathy Disease Progression Disease susceptibility Genetic aspects Genotype & phenotype Glomerular Filtration Rate Glucose Health aspects Humans Hyperglycemia Hypertension Kidney - pathology Kidney diseases Medical research Medicine Medicine & Public Health Medicine, Experimental Nephrology Phenotype Remission (Medicine) Renal Insufficiency, Chronic - etiology Renal Insufficiency, Chronic - metabolism Renal Insufficiency, Chronic - physiopathology Review Article Severity of Illness Index Time Factors
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