Association between circulating bile acid alterations and nonalcoholic steatohepatitis independent of obesity and diabetes mellitus

Background and Aims Bile acid (BA) dysregulation is related to not only metabolic diseases but also nonalcoholic fatty liver disease (NAFLD). We investigated whether circulating BA levels are altered according to the histological severity of NAFLD independent of metabolic derangements. Methods Globa...

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Veröffentlicht in:	Liver international 2021-12, Vol.41 (12), p.2892-2902
Hauptverfasser:	Jung, Youngae, Koo, Bo Kyung, Jang, Seo Young, Kim, Dain, Lee, Heeyeon, Lee, Dong Hyeon, Joo, Sae Kyung, Jung, Yong Jin, Park, Jeong Hwan, Yoo, Taekyeong, Choi, Murim, Lee, Min Kyung, Kang, Sang Won, Chang, Mee Soo, Kim, Won, Hwang, Geum‐Sook
Format:	Artikel
Sprache:	eng
Schlagworte:	aqueous metabolites bile acid Bile Acids and Salts - metabolism Biopsy Body mass Body mass index Body size Diabetes Diabetes Mellitus Fatty liver fibrosis Humans Liver Liver - pathology Liver diseases Metabolic disorders Metabolism Metabolites Non-alcoholic Fatty Liver Disease - complications nonalcoholic steatohepatitis nonobese Obesity Obesity - complications Obesity - metabolism Phenotypes Transcriptomes
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