Depletion of circRNA circ_CDK14 inhibits osteosarcoma progression by regulating the miR-520a-3p/GAB1 axis

Osteosarcoma (OS) is a lethal bone malignancy. Circular RNAs (circRNAs) have emerged as important regulators of OS development. CircRNA cyclin dependent kinase 14 (circ_CDK14) was reported to be a potential oncogene in OS. However, the mechanistic pathway by which circ_CDK14 functions in OS is large...

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Veröffentlicht in:	Neoplasma 2021-01, Vol.68 (4), p.798-809
Hauptverfasser:	Wu, Peng-Fei, Tang, Xiao-Ming, Sun, Hai-Lang, Jiang, Hai-Tao, Ma, Jian, Kong, Ying-Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Cell Line, Tumor Cyclin-Dependent Kinases Gene Expression Regulation, Neoplastic Humans MicroRNAs - genetics Osteosarcoma - genetics RNA, Circular
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