Persistent changes in exploration and hyperactivity coexist with cognitive impairment in mice withdrawn from chronic cocaine

Repeated cocaine exposure induces lasting neurobehavioral adaptations such as cognitive decline in animal models. However, persistent changes in spontaneous –unconditioned- motor and exploratory responses are scarcely reported. In this study, mice were administered with cocaine (20 mg/kg/day) or veh...

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Veröffentlicht in:	Physiology & behavior 2021-10, Vol.240, p.113542-113542, Article 113542
Hauptverfasser:	Mañas-Padilla, M. Carmen, Ávila-Gámiz, Fabiola, Gil-Rodríguez, Sara, Ladrón de Guevara-Miranda, David, Rodríguez de Fonseca, Fernando, Santín, Luis J., Castilla-Ortega, Estela
Format:	Artikel
Sprache:	eng
Schlagworte:	Anxiety Elevated plus maze Forced swimming Place recognition memory Spatial working memory
Online-Zugang:	Volltext
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