Systematic Review and Meta-Analysis of Hardware Failure in Surgical Stabilization of Rib Fractures: Who, What, When, Where, and Why?

•Pooled prevalence of hardware failure after surgical stabilization of rib fractures is 4 (95% CI:3-7)%.•Meta-regression shows fracture acuity (acute compared to chronic) is a significant moderator of hardware failure•Mechanical failures are the most common type of reported hardware failures•Approxi...

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Veröffentlicht in:The Journal of surgical research 2021-12, Vol.268, p.190-198
Hauptverfasser: Choi, Jeff, Kaghazchi, Aydin, Sun, Beatrice, Woodward, Amanda, Forrester, Joseph D.
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Sprache:eng
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Zusammenfassung:•Pooled prevalence of hardware failure after surgical stabilization of rib fractures is 4 (95% CI:3-7)%.•Meta-regression shows fracture acuity (acute compared to chronic) is a significant moderator of hardware failure•Mechanical failures are the most common type of reported hardware failures•Approximately 60% of patients underwent hardware removal after hardware failure•Where and why hardware failures occur require further investigation Surgical stabilization of rib fractures (SSRF) is increasingly used to reduce pulmonary complications and death among patients with rib fractures. However, the five Ws of hardware failure –who, what, when, where, and why– remains unclear. We aimed to synthesize available evidence on the five Ws and outline future research agenda for mitigating hardware failure. Experimental and observational studies published between 2009 and 2020 evaluating adults undergoing SSRF for traumatic rib fractures underwent evidence synthesis. We performed random effects meta-analysis of cohort/consecutive case studies. We calculated pooled prevalence of SSRF hardware failures using Freeman-Tukey double arcsine transformation and assessed study heterogeneity using DerSimonian-Laird estimation. We performed meta-regression with rib fracture acuity (acute or chronic) and hardware type (metal plate or not metal plate) as moderators. Twenty-nine studies underwent qualitative synthesis and 24 studies (2404 SSRF patients) underwent quantitative synthesis. Pooled prevalence of hardware failure was 4(3-7)%. Meta-regression showed fracture acuity was a significant moderator (P = 0.002) of hardware failure but hardware type was not (P = 0.23). Approximately 60% of patients underwent hardware removal after hardware failure. Mechanical failures were the most common type of hardware failure, followed by hardware infections, pain/discomfort, and non-union. Timing of hardware failure after surgery was highly variable, but 87% of failures occurred after initial hospitalization. Mechanical failures was attributed to technical shortcomings (i.e. short plate length) or excessive force on the thoracic cavity. SSRF hardware failure is an uncommon complication. Not all hardware failures are consequential, but insufficient individual patient data precluded characterizing where and why hardware failures occur. Minimizing SSRF hardware failure requires concerted research agenda to expand on the paucity of existing evidence.
ISSN:0022-4804
1095-8673
DOI:10.1016/j.jss.2021.06.054