Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness

Traditional Chinese Medicine (TCM) is being increasingly used worldwide due to its diverse efficacy and relatively low side effects. Babao Dan (BBD) is a well-known TCM formula that is currently used for the effective treatment of various cancers, however its underlying molecular mechanism remains u...

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Veröffentlicht in:	Journal of ethnopharmacology 2021-11, Vol.280, p.114449-114449, Article 114449
Hauptverfasser:	Xie, Xinxin, Chen, Jinxiao, Wo, Da, Ma, En, Ning, Yongling, Peng, Jun, Zhu, Weidong, Ren, Dan-ni
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Tumor Antineoplastic Agents, Phytogenic - pharmacology Babao dan beta Catenin - genetics Cancer stem cell Cell Proliferation - drug effects Drugs, Chinese Herbal - pharmacology EpCAM Hep G2 Cells Hepatoblastoma Hepatoblastoma - drug therapy Hepatoblastoma - genetics Hepatoblastoma - pathology Humans Liver Neoplasms - drug therapy Liver Neoplasms - genetics Liver Neoplasms - pathology Male Mice Mice, Inbred BALB C Mice, Nude Mutation Neoplastic Stem Cells - drug effects Wnt Signaling Pathway - drug effects Wnt/β-catenin signaling Xenograft Model Antitumor Assays
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