IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia

The morbidity and mortality of myeloproliferative neoplasms (MPNs) are primarily caused by arterial and venous complications, progression to myelofibrosis, and transformation to acute leukemia. However, identifying molecular-based biomarkers for risk stratification of patients with MPNs remains a ch...

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Veröffentlicht in:	Frontiers of medicine 2022-06, Vol.16 (3), p.403-415
Hauptverfasser:	Huang, Xiao, Ma, Tingting, Zhu, Yongmei, Jiao, Bo, Yu, Shanhe, Wang, Kankan, Mi, Jian-Qing, Ren, Ruibao
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers essential thrombocythemia Genotype & phenotype hydroxyurea IRF4 IRF8 Medicine Medicine & Public Health myeloproliferative neoplasms Research Article
Online-Zugang:	Volltext
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