Extracellular metabolism of 3′,5′-cyclic AMP as a source of interstitial adenosine in the rat airways

[Display omitted] In the respiratory tract, intracellular 3′,5′-cAMP mediates smooth muscle relaxation triggered by the β2-adrenoceptor/Gs protein/adenylyl cyclase axis. More recently, we have shown that β2-adrenoceptor agonists also increase extracellular 3′,5′-cAMP levels in isolated rat trachea,...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemical pharmacology 2021-10, Vol.192, p.114713-114713, Article 114713
Hauptverfasser:	Pacini, Enio Setsuo Arakaki, Jackson, Edwin Kerry, Godinho, Rosely Oliveira
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Airways Cyclic AMP Ecto-phosphodiesterase Inosine Smooth muscle
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!