Associations between dietary intake of B vitamins and cardiovascular risk factors in elderly men: A cross‐sectional study

Objective Low intake of B vitamins can lead to hyperhomocysteinaemia, which is reported as a risk factor for cardiovascular disease (CVD). However, little is known about this relationship. Therefore, we decided to examine the association between dietary intake of B vitamins and cardiovascular risk f...

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Veröffentlicht in:International journal of clinical practice (Esher) 2021-10, Vol.75 (10), p.e14691-n/a
Hauptverfasser: Mozaffari, Hadis, Askari, Mohammadreza, Bellissimo, Nick, Azadbakht, Leila
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Sprache:eng
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Zusammenfassung:Objective Low intake of B vitamins can lead to hyperhomocysteinaemia, which is reported as a risk factor for cardiovascular disease (CVD). However, little is known about this relationship. Therefore, we decided to examine the association between dietary intake of B vitamins and cardiovascular risk factors in elderly men. Methods The present cross‐sectional study consisted of 357 elderly men. Dietary intake was assessed using a validated and reliable food frequency questionnaire. All biochemical factors [fasting blood sugar (FBS), triglyceride (TG), high‐sensitivity C‐reactive protein (hs‐CRP), interleukin 6 (IL‐6) and tumour necrosis factor‐α (TNF‐α)], waist circumference (WC) and blood pressure (BP) were assessed using standard methods. Results A significant inverse association was observed between high dietary intake of total B vitamins (ORTotal B vitamins: 0.30; 95% CI: 0.10, 0.86; P = .01) and vitamin B9 (ORvitamin B9: 0.20; 95% CI: 0.02, 0.52; P = .002) with high WC. Furthermore, an inverse association was observed between high dietary intake of vitamin B6 (ORvitamin B6: 0.28; 95% CI: 0.08, 1.00; P = .05) and vitamin B9 (ORvitamin B9: 0.20; 95% CI: 0.06, 0.70; P = .01) with hs‐CRP level. Conclusions In elderly men, a high dietary intake of total B vitamins and vitamin B9 was associated with lower odds of having a high WC. Similarly, high dietary intake of vitamin B6 and B9 was associated with lower odds of having a high hs‐CRP level.
ISSN:1368-5031
1742-1241
DOI:10.1111/ijcp.14691