Transcriptional and posttranslational regulation of Th17/Treg balance in health and disease

Regulatory T (Treg) cells and T helper type 17 (Th17) cells play important roles in adaptive immune responses, antagonizing each other in immune disorders. Th17/Treg balance is critical to maintaining the immune homeostasis of human bodies and is tightly regulated under healthy conditions. The trans...

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Veröffentlicht in:	European journal of immunology 2021-09, Vol.51 (9), p.2137-2150
Hauptverfasser:	Zhang, Weiqi, Liu, Xu, Zhu, Yicheng, Liu, Xinnan, Gu, Yunting, Dai, Xueyu, Li, Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Cell differentiation Cofactors Enzymatic activity Foxp3 protein Gene regulation Helper cells Homeostasis immune homeostasis Immune response Inflammatory diseases Lymphocytes T Microenvironments posttranslational modification Th17/Treg balance Transcription factors
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