Circ_0007031 Silencing Inhibits Cell Proliferation and Induces Cell Apoptosis via Downregulating MELK at a miR-485-3p-Dependent Way in Colorectal Cancer

Colorectal cancer (CRC) is a malignant cancer with an increasing incidence. Circular RNA (circRNA) is recently found to participate in the regulation of CRC progression. However, the role of circ_0007031 in CRC malignant progression remains elusive. 50 CRC patients were implicated in this study. Qua...

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Veröffentlicht in:	Biochemical genetics 2022-04, Vol.60 (2), p.576-597
Hauptverfasser:	Su, Shengtian, Lu, Wenjing, Liu, Jun, Li, Liping, Liu, Liang, Li, Xiaoju, Ye, Dan, Yu, Zhigao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - genetics Assaying Biochemistry Biomedical and Life Sciences Biomedicine Cancer Cell cycle Cell growth Cell proliferation Cell Proliferation - genetics Cell viability Circular RNA Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - metabolism Embryos Flow cytometry G1 phase Gene expression Human Genetics Humans Kinases Leucine Leucine zipper proteins Malignancy Medical Microbiology Mice MicroRNAs - genetics MicroRNAs - metabolism miRNA Original Article Polymerase chain reaction Protein Serine-Threonine Kinases Ribonucleic acid RNA RNA, Circular - genetics S phase Tumors Zoology
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