Identification of miRNA signatures and their therapeutic potentials in prostate cancer

Background Herein, we identified miRNA signatures that were able to differentiate malignant prostate cancer from benign prostate hyperplasia and revealed the therapeutic potential of these miRNAs against prostate cancer development. Methods and results MicroRNA expressions were determined by qPCR. M...

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Veröffentlicht in:	Molecular biology reports 2021-07, Vol.48 (7), p.5531-5539
Hauptverfasser:	Karadag, Abdullah, Ozen, Ata, Ozkurt, Mete, Can, Cavit, Bozgeyik, Ibrahim, Kabadere, Selda, Uyar, Ruhi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animal Anatomy Animal Biochemistry Bax protein Bcl-2 protein Biomarkers, Tumor Biomedical and Life Sciences Caspase-3 Cell Line, Tumor Cell migration Cell proliferation Cell viability Circulating MicroRNA Computational Biology - methods Cytology Disease Management Disease Susceptibility Ectopic expression Enzyme-Linked Immunosorbent Assay Gelatinase A Gelatinase B Gene Expression Profiling Gene Expression Regulation, Neoplastic Histology Humans Hyperplasia Immunohistochemistry Life Sciences Male MicroRNAs MicroRNAs - genetics Middle Aged miRNA Morphology Neoplasm Metastasis Neoplasm Staging Original Article Prognosis Prostate cancer Prostatic Neoplasms - diagnosis Prostatic Neoplasms - genetics Prostatic Neoplasms - therapy Transcriptome Wound healing
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