Protective effect of MSC-derived exosomes against cisplatin-induced apoptosis via heat shock protein 70 in auditory explant model

Therapeutics based on stem cell technology, including stem cell-derived exosomes, have emerged in recent years for the treatment of what were otherwise considered incurable diseases. In this study, we evaluated the efficacy of human MSC-derived exosomes for protection against cisplatin induced ototo...

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Veröffentlicht in:	Nanomedicine 2021-11, Vol.38, p.102447-102447, Article 102447
Hauptverfasser:	Park, Dong Jun, Park, Jeong-Eun, Lee, Su Hoon, Eliceiri, Brian P., Choi, Jin Sil, Seo, Young Joon
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cisplatin Cisplatin - adverse effects Cisplatin - metabolism Cochlea explant Exosomes - metabolism Hearing loss HSP70 HSP70 Heat-Shock Proteins - metabolism Humans Mesenchymal Stem Cells - metabolism MSC derived exosome
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