On the prevention and treatment of Alzheimer’s disease: Control the promoters and look beyond the brain

Alzheimer’s disease (AD) is a progressive incurable neurodegenerative disease of the brain afflicting a third of the population aged 85 and older. Pathologic hallmarks include extracellular plaques of amyloid-beta (Aß), intraneuronal neurofibrillary tangles of hyperphosphorylated tau protein, synapt...

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Veröffentlicht in:	Medical hypotheses 2021-09, Vol.154, p.110645-110645, Article 110645
Hauptverfasser:	Goldstein, Mark R., Cheslock, Megan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer’s disease Amyloid-beta ApoE Cerebral amyloid angiopathy Dementia Down syndrome HSV Microglia Neuroinflammation Periodontal disease Tau
Online-Zugang:	Volltext
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