Loss of longitudinal superiority marks the microarchitecture deterioration of osteoporotic cancellous bones

Osteoporosis (OP), a skeletal disease making bone mechanically deteriorate and easily fracture, is a global public health issue due to its high prevalence. It has been well recognized that besides bone loss, microarchitecture degradation plays a crucial role in the mechanical deterioration of OP bon...

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Veröffentlicht in:	Biomechanics and modeling in mechanobiology 2021-10, Vol.20 (5), p.2013-2030
Hauptverfasser:	Li, Zhenzi, Liu, Pan, Yuan, Yanan, Liang, Xiaoxiao, Lei, Jun, Zhu, Xiaobin, Zhang, Zuoqi, Cai, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anisotropy Biological and Medical Physics Biomedical Engineering and Bioengineering Biomedical materials Biophysics Bone and Bones Bone loss Bone mass Bones Cancellous Bone - physiopathology Computer architecture Degradation Engineering Female Finite Element Analysis Finite element method Health care Imaging, Three-Dimensional Lumbar Vertebrae - physiopathology Mechanical loading Mechanical properties Mice Mice, Inbred BALB C Original Paper Osteoporosis Osteoporosis - physiopathology Osteoporotic Fractures - physiopathology Ovariectomy Porosity Pressure Public health Stiffness Stress, Mechanical Theoretical and Applied Mechanics Topology X-Ray Microtomography - methods
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