HNRNPU-AS1 Regulates Cell Proliferation and Apoptosis via the MicroRNA 205-5p/AXIN2 Axis and Wnt/β-Catenin Signaling Pathway in Cervical Cancer

Long noncoding RNAs (lncRNAs) have key functions in modulating cervical cancer (CC) genesis and progression. This work focused on exploring lncRNA HNRNPU-AS1's function in CC and the underlying mechanism. HNRNPU-AS1, AXIN2, and microRNA 205-5p (miR-205-5p) levels in CC cases were measured throu...

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Veröffentlicht in:	Molecular and cellular biology 2021-09, Vol.41 (10), p.e0011521-e0011521
Hauptverfasser:	Niu, Zhaoyuan, Wang, Fengling, Lv, Shihui, Lv, Yingpin, Liu, Ming, Fu, Lei, Yao, Yushuang, Wang, Lingzhi, Lin, Wei, Yuan, Fang
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis Apoptosis - genetics Axin Protein - genetics AXIN2 beta Catenin - genetics Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics cervical cancer Female Gene Expression - genetics Gene Expression Regulation, Neoplastic - genetics Heterogeneous-Nuclear Ribonucleoprotein U - genetics HNRNPU-AS1 Humans MicroRNAs - genetics miR-205-5p Molecular and Cellular Biology Prognosis proliferation Research Article RNA, Antisense - genetics RNA, Long Noncoding - genetics Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - metabolism Uterine Cervical Neoplasms - physiopathology Wnt Signaling Pathway - genetics Wnt/β-catenin
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