Predicting lubricants effect on tablet sticking using ketoprofen as model drug and evaluating sticking propensity using different metals and powder rheology

[Display omitted] •Powder rheology technique can be utilized to predict tablet sticking.•Sticking index can be used to select formulation and punch metal to avoid sticking.•Lubricant helps reducing the tablet sticking at some extent.•Formulation’s cohesive and adhesive properties to the punch metal...

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Veröffentlicht in:	International journal of pharmaceutics 2021-09, Vol.606, p.120913-120913, Article 120913
Hauptverfasser:	Patel, Devang B., Dave, Rutesh H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Lubricant Powder rheology Punch metals Sticking index Tablet sticking Wall friction
Online-Zugang:	Volltext
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