mTORC1 Signaling Regulates Proinflammatory Macrophage Function and Metabolism

Metabolic programming is integrally linked to immune cell function. Nowhere is this clearer than in the differentiation of macrophages. Proinflammatory M1 macrophages primarily use glycolysis as a rapid energy source but also to generate antimicrobial compounds, whereas alternatively activated M2 ma...

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Veröffentlicht in:	The Journal of immunology (1950) 2021-08, Vol.207 (3), p.913-922
Hauptverfasser:	Collins, Samuel L., Oh, Min-Hee, Sun, Im-Hong, Chan-Li, Yee, Zhao, Liang, Powell, Jonathan D., Horton, Maureen R.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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