Anti-inflammatory TNF receptor 2 signalling unravelled

Anti-inflammatory TNF receptor 2 signalling unravelled

A new study describes an anti-inflammatory signalling pathway mediated by TNFR2 and the signalling molecule 14-3-3ε and the effects of this pathway on macrophage polarization.

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Bibliographische Detailangaben
Veröffentlicht in:Nature reviews. Rheumatology 2021-09, Vol.17 (9), p.509-509
1. Verfasser: Clarke, Joanna
Format: Artikel
Sprache:eng
Schlagworte:
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692/308/575
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Autoimmunity
Cellular signal transduction
Cytokine receptors
Development and progression
Health aspects
Immunological research
Inflammation
Macrophages
Medicine
Medicine & Public Health
Physiological aspects
Research Highlight
Rheumatology
Signal transduction
Tumor necrosis factor
Tumor necrosis factor receptors
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Beschreibung
Zusammenfassung:A new study describes an anti-inflammatory signalling pathway mediated by TNFR2 and the signalling molecule 14-3-3ε and the effects of this pathway on macrophage polarization.
ISSN:1759-4790
1759-4804
DOI:10.1038/s41584-021-00669-0