H3K27Ac modification and gene expression in psoriasis

•There is a differential H3K27Ac pattern between psoriatic to healthy skin.•There is a differential H3K27Ac pattern between psoriatic to uninvolved skin.•In most overexpressed genes in psoriasis, there is an enrichment of H3K27Ac.•Decreased gene expression in psoriasis does not correlate with decrea...

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Veröffentlicht in:	Journal of dermatological science 2021-08, Vol.103 (2), p.93-100
Hauptverfasser:	Masalha, Moamen, Ben-Dov, Iddo Z., Ram, Oren, Meningher, Tal, Jacob-Hirsch, Jasmine, Kassem, Riad, Sidi, Yechezkel, Avni, Dror
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation of the histone H3 at lysine 27 (H3K27Ac) Case-Control Studies Chromatin immunoprecipitation sequencing (ChIP-seq) Epigenetics Gene Expression Histone Code Humans Psoriasis Psoriasis - etiology Psoriasis - metabolism Transcription factor Transcription Factors - metabolism
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